Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis
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چکیده
منابع مشابه
Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis
Objectives—Intraventricular astrocytomas (subependymal giant cell astrocytomas) of tuberous sclerosis have a poor prognosis due to the obstruction of CSF flow. The aim of this study was to determine whether they could be diVerentiated during childhood and at an early preclinical stage, from subependymal nodules without any growing potential. Methods—The first two MRIs of all children referred t...
متن کاملEarly diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis.
OBJECTIVES Intraventricular astrocytomas (subependymal giant cell astrocytomas) of tuberous sclerosis have a poor prognosis due to the obstruction of CSF flow. The aim of this study was to determine whether they could be differentiated during childhood and at an early preclinical stage, from subependymal nodules without any growing potential. METHODS The first two MRIs of all children referre...
متن کامل[Subependymal giant cell astrocytoma (tuberous sclerosis)].
Two cases of tuberous sclerosis with subependymal giant cell astrocytoma are presented. This rare autosomal dominant disorder was also detected in family members of the patients who had never had any symptoms of cerebral involvement. Both patients underwent surgery because of signs of increased intracranial pressure.
متن کاملRegression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex.
The authors present a 21-year-old woman who has been receiving rapamycin for 5 months for bilateral subependymal giant cell astrocytomas. The patient was started at a dose of 0.2 mg/kg/day. Levels were maintained between 11 and 13 ng/mL. Magnetic resonance imaging of the brain 2(1/2) months after initiating rapamycin demonstrated a decrease in size of both astrocytomas (11 to 7.5 mm on the righ...
متن کاملRare subependymal giant-cell astrocytoma in a neonate with tuberous sclerosis.
The patient was a full-term 3-day-old male infant. From birth , he had been lethargic and had had seizures. CT showed a large left frontal horn and mass in the foramen of Monro with left unilateral hydrocephalus and both subependymal and parenchymal nodules. The tumor and these nodules were hyperdense on unenhanced CT scans, and contrast-enhanced scans showed mild enhancement (Figs. 1 A and 1 B...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2000
ISSN: 0022-3050
DOI: 10.1136/jnnp.68.1.118a